(no subject)
Oct. 16th, 2006 01:09 amFor
gypsy_raihana, who has probably already seen it:
Mutated gene doubles autism risk, study finds
Researchers find first clear genetic link to the complex disorder
Reuters
Updated: 6:16 p.m. CT Oct 16, 2006
WASHINGTON - U.S. researchers said on Monday they had identified a genetic mutation that raises the risk of autism and could also explain some of the other symptoms seen in children with autism.
Although autism and similar disorders can clearly run in families, theirs is the first study to find a definitive genetic link to the disorder, which affects as many as 1 in 175 U.S. children.
Dr. Pat Levitt and colleagues at Vanderbilt University in Nashville, Tenn., studied 743 families in which 1,200 family members were affected by autism spectrum disorders, which range from fully disabling autism to Asperger’s syndrome.
They found a single mutation in a gene called MET, which is known to be involved in brain development, regulation of the immune system and repair of the gastrointestinal system. All of these systems can be affected in children with autism.
“This is a vulnerability gene,” Levitt said. “There are not genes that actually cause autism. It raises the risk.”
2 copies of gene double the risk
People with two copies of the mutated gene have 2 to 2.5 times the normal risk of autism and people with one mutated copy have 1.7 times the risk, he said.
The findings, published in the Proceedings of the National Academy of Sciences, offer a way to start looking for the actual causes of autism, Levitt said.
( Read more... )
![[livejournal.com profile]](https://www.dreamwidth.org/img/external/lj-userinfo.gif)
Mutated gene doubles autism risk, study finds
Researchers find first clear genetic link to the complex disorder
Reuters
Updated: 6:16 p.m. CT Oct 16, 2006
WASHINGTON - U.S. researchers said on Monday they had identified a genetic mutation that raises the risk of autism and could also explain some of the other symptoms seen in children with autism.
Although autism and similar disorders can clearly run in families, theirs is the first study to find a definitive genetic link to the disorder, which affects as many as 1 in 175 U.S. children.
Dr. Pat Levitt and colleagues at Vanderbilt University in Nashville, Tenn., studied 743 families in which 1,200 family members were affected by autism spectrum disorders, which range from fully disabling autism to Asperger’s syndrome.
They found a single mutation in a gene called MET, which is known to be involved in brain development, regulation of the immune system and repair of the gastrointestinal system. All of these systems can be affected in children with autism.
“This is a vulnerability gene,” Levitt said. “There are not genes that actually cause autism. It raises the risk.”
2 copies of gene double the risk
People with two copies of the mutated gene have 2 to 2.5 times the normal risk of autism and people with one mutated copy have 1.7 times the risk, he said.
The findings, published in the Proceedings of the National Academy of Sciences, offer a way to start looking for the actual causes of autism, Levitt said.
( Read more... )